Can testosterone affect the kidneys? Testosterone affects everything in a male, hence the answer is 'yes'. Most men on HRT (testosterone therapy) may not be aware of several counterintuitive ways in which testosterone can affect the kidneys. One is generally positive and the other generally negative. In some cases testosterone replacement therapy could actually aggravate or harm the kidneys in certain sensitive men.
To go too high in their testosterone level when they are on HRT, it is one thing many men probably do not want. Consider this discussion below:
1. Erythropoietin. In the bone marrow and testosterone ramps both erythropoietin and red blood cell production upwards significantly for triggering your red blood cell production, this kidney hormone is responsible. Hematocrit or haemoglobin does not go too high In fact, low testosterone men are quite often anaemic men who go on HRT need to monitor to make sure their RBC count because of it and. This can have some serious consequences.
Does simply raising erythropoietin cause any issues with the kidneys? Well, not directly. Testosterone therapy can further raise their blood pressure, for which there is evidence that in some men with hypertension. The delicate vessels in the kidneys can get injured and an increase in blood pressure can potentially, over time. Kidneys struggle to do their job and eliminate wastes, etc when these blood vessels get injured. This can lead to an increase in fluids. Are you sensing a vicious cycle here? Yes, as the fluids increase, blood pressure increases and so on. This can be a big problem for diabetics and men with advanced kidney disease.
NOTE: One interesting fact about erythropoietin is that it is also called EPO, a name that may be more familiar to some of you. Yes, that should bring the name Lance Armstrong to mind. Strictly for the purpose of raising his red blood cell counts for racing purposes, Lance Armstrong confessed to Using EPO as a performance-enhancing drug. Basically, a different and very dangerous kind of steroid was being used. Dying in their sleep from the "sludging" of the blood that occurs giving EPO to these Racers leaves them vulnerable to. It does turn them into super-humans however.
2. Contraindicated for Advanced Kidney Disease. Testosterone therapy not is given to men with kidney disease as per some sources recommendations, even if they are hypogonadal, some sources say Testosterone could potentially aggravate or inflame the kidneys for these men according to their thinking, this is the reason for that. Experts would not take chances in those who are vulnerable, healthy men can hold this process in check without chronic injury.
Apoptotic damage in human renal tubular cells is the primary reason that testosterone appears to promote several animal studies showed this effect and then researchers repeated the test in vitro. Apoptosis basically refers to Programmed cell death. Many kinds of cells that have been latent within them. Testosterone basically accelerates this condition according to the above anyway.
For those with kidney issues whether testosterone may be questionable: Further study work has identified other key ways that
a) "Increase tubular sodium"
b) "Water reabsorption"
c) "Activate the renin-angiotensin system and endothelin as a part of various vasoconstrictor systems in the kidney.
d) " Increase oxidative stress." 
So clearly testosterone has the potential to be hard on the kidneys. But, again, you just do not see men struggling with kidney issues on TRT (testosterone replacement therapy). Talk to your doctor, though, and get his or her opinion.
Furthermore, I don't believe we have had a single legitimate complaint of a kidney issue on the Peak Testosterone Forum related to testosterone therapy. We had one man who thought he had an issue actually:
"Can the shot cause kidney issues?? Ever since I got the shot on Thursday in my right hip. A constant pain almost like I got a kidney stone my left kidney lower back has had. My tongue feeling like it was too big for my mouth and the 1st shot I had issues with. Now, this. Any ideas?
However, it turned out that he had a small kidney stone!
Bottom line: get screened before and after for kidney function and discuss with your physician. How do you check kidney function? Here are some or all of the standard tests well, this is a big subject of course, but: GFR (Glomerular Filtration Rate) and creatinine clearance.
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Male Sexuality and Chronic Kidney Disease
Chronic kidney disease (CKD) Sexuality has both physical and emotional components. Chemical changes can occur in the body affecting circulation, nerve function, hormones and energy level due to Kidney disease. CKD like high blood pressure or diabetes can affect male sexuality and also, any underlying health conditions that are contributed.
Too tired for sex?
Men with kidney disease experience Fatigue as one of the most common symptoms. In the early stages of CKD, low levels of waste and fluid remain in the body. This can make you feel tired and sluggish. Your doctor can perform tests to determine how much kidney function you have left. Your doctor may refer you to a renal dietician if you are in the later stages of CKD or end-stage renal disease (ESRD). A kidney-friendly diet designed to limit the amount of waste that can build up in your body will be placed you on by the dietician. The better you will feel when lesser the waste and fluid in your system.
After their hemodialysis session, people with ESRD may feel really tired. If you are new to hemodialysis, it may take several treatments for your body to adjust. Ongoing fatigue should be discussed with your doctor and renal dietician. Your dialysis treatment or medicines can be changed by your doctor who can recommend changes in the treatment schedule. Your renal dietitian can help you go over your food and fluid intake and make any needed changes.
Low sex drive
Chemicals produced by the body's endocrine system are hormones. A person's ability to feel sexual desire plays a major role. The kidneys are part of the endocrine system. Certain hormones are produced by the adrenal glands, located at the top of each kidney. You may experience a decrease in your sex drive if hormone levels become out of balance.
Whether your lack of interest in sex is due to your changing hormone levels, your doctor can perform blood work to determine. Your levels might be brought to a normal range by prescribing medicines.
Even those without kidney disease Erectile dysfunction (ED), commonly called "impotence," affects many men. Impotence affects an estimated 20 to 30 million men in the U.S. and has problems with. ED can happen when blood vessels and nerves to the penis become damaged. To maintain an erection, the penis should have a proper blood flow.
Diabetes and high blood pressure affect blood flow and weaken blood vessels. If you have either of these conditions, follow your doctor's treatment plan to prevent further damage.
Particularly those taken to control blood pressure, sometimes ED is a side effect of medicines. Talk to your doctor about the medicines you're taking if you're experiencing impotence. To make changes to your medications or suggest treatments for impotence, your doctor may be able to make psychological effects of CKD on men's sexuality.
Sexuality is not just about sexual intercourse. It's also about how people express themselves and feel towards ourselves. When the body undergoes unexpected changes, feeling sexual or attractive becomes more difficult. Their ability to develop intimate relationships and this can affect how people interact with Body image and others.
Breath and body odour, complexion problems, weight gain or unusual facial or body hair can occur making them feel less attractive with varied symptoms as mentioned. People with CKD may experience some undesirable changes to their bodies. How his vascular access site looks and feels a man on hemodialysis may feel self-conscious about. Size of their abdomens is a matter of worry for men on peritoneal dialysis (PD). Discuss with your partner and your healthcare team any uncomfortable physical changes. Some physical changes are temporary, while others may indicate a health complication.
Worry and stress
When faced with CKD, men may feel worried, anxious and depressed. This may cause loss of energy and lower interest in activities, including sex, this is normal, including these emotions.
Tell your doctor and social worker immediately if feelings of depression or sadness last for more than two weeks,
Some men feel mutual sexual activity may be harmful to their condition or harmful to their partners. Speak to your doctor about your concerns some men are afraid. sexual intercourse may not be possible in very rare instances. Even if intercourse is not involved, activities such as touching, hugging and kissing provide feelings of warmth and closeness. Alternative methods of sexual expression can be recommended by Professional sex therapists.
Your healthcare team is there to answer any questions you may have. Consider joining an in-person support group or an online group to talk with others who are in similar circumstances. Visit the DaVita Discussion Forum to see what others are talking about, ask questions and share experiences.
Chronic kidney disease
Gradual loss of kidney function or Chronic kidney disease, also called chronic kidney failure, describes the loss of kidney function. Wastes and excess fluids from your blood, which are then excreted in your urine your kidneys filter. Dangerous levels of fluid, electrolytes and wastes can build up in your body when chronic kidney disease reaches an advanced stage.
You may have only aa few signs or symptoms in the early stages of chronic kidney disease. Chronic kidney disease may not become apparent until your kidney function is significantly impaired.
Slowing the progression of the kidney damage, usually by controlling the underlying cause treatment for chronic kidney disease focuses on. It is fatal without artificial filtering (dialysis) or a kidney transplant, chronic kidney disease can progress to end-stage kidney failure.
If kidney damage progresses slowly as compared to a fast deterioration, signs and symptoms of chronic kidney disease develop slowly over and there will be no quick signs. Signs and symptoms of kidney disease may include:
Vomiting of appetite
Fatigue and weakness
Changes in how much you urinate
Decreased mental sharpness
Muscle twitches and cramps
Swelling of feet and ankles
If fluid builds up around the lining of the heart Chest pain forms progressively,
Shortness of breath, if fluid builds up in the lungs
Difficult to control High blood pressure (hypertension)
They can also be caused by other illnesses, often nonspecific signs and symptoms of kidney disease are. Because your kidneys are highly adaptable and able to compensate for lost function, signs and symptoms may not appear until irreversible damage has occurred.
When to see a doctor
If you have any signs or symptoms of kidney disease, make an appointment with your doctor.
Your doctor is likely to monitor your blood pressure and kidney function with urine and blood tests during regular office visits if you have a medical condition that increases your risk of kidney disease. Ask your doctor whether these tests are necessary for you.
Illustration showing normal kidney compared with diseased kidney
Normal kidney vs. diseased kidney
Polycystic kidney compared with normal kidney
Causing kidney damage to worsen over several months or years, chronic kidney disease occurs when a disease or condition impairs kidney function.